Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repression
نویسندگان
چکیده
منابع مشابه
Myc-mediated transcriptional repression by recruitment of histone deacetylase.
Myc is a transcription factor that features prominently in cancer. The oncogenicity of Myc stems from its ability to regulate expression of genes required for cell growth and proliferation. Although the mechanisms through which Myc activates transcription have been extensively studied, less is known about how Myc represses transcription. Recently, we reported that a conserved element within Myc...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2002
ISSN: 0890-9369
DOI: 10.1101/gad.962502